Amazon S3 + bulkloader = use a LoaderContext!
In an attempt to save you hours of painful debugging and Adobe-hating: if you're wanting to use the excellent AS3 bulk-loader lib to load assets from S3, follow these steps. Especially step 2.
1. Put your normal crossdomain.xml in place in your S3 bucket
2. Use a loader context on every BulkLoader !
var context:LoaderContext = new LoaderContext(true, ApplicationDomain.currentDomain);
var loader:BulkLoader = new BulkLoader("loadmystuffplskthxbye");
loader.add( someS3Url, { context: context } ); // WIN
reference: http://developer.amazonwebservices.com/connect/entry.jspa?externalID=2011
Update: as @koblongata and @Jinx posted in the comments, you'll also want to use this technique when loading from Flickr, Facebook or presumably any other API.